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Organic Compounds -- Part Of The Class 532-570 Series > Azo Compounds Containing Formaldehyde Reaction Product As The Coupling Component > Carbohydrates Or Derivatives > Nitrogen Containing > Dna Or Rna Fragments Or Modified Forms Thereof (e.g., Genes, Etc.) Dna Or Rna Fragments Or Modified Forms Thereof (e.g., Genes, Etc.)Dna Or Rna Fragments Or Modified Forms Thereof (e.g., Genes, Etc.) patent applications listed are from June 2005 to current and include Date, Patent Application Number, Patent Title, Patent Abstract summary and are linked to the corresponding patent application page.01/04/07 - 20070004911 - Silylated oligonucleotide compounds Oligonucleotide comprising at least one internucleotide phosphorus atom protected with a group of formula —XaSiR3R4R5 provided. Xa represent 0 or S, and R3, R4 and R5 each independently are optionally substituted hydrocarbyl groups, selected such that that total number of carbon atoms in R3 plus R4 plus R5 is 4 ... 12/28/06 - 20060293511 - Phosphinoamidite carboxylates and analogs thereof in the synthesis of oligonucleotides having reduced internucleotide charge in which W, X, Y, Z, R1 and n are as defined herein. ... 12/28/06 - 20060293510 - Metal complex type nucleic acid The present invention relates to a double-stranded oligonucleotide derivative, which contains two oligonucleotide derivatives each containing at least one nucleotide derivative wherein a base portion of a nucleotide is substituted with a metal coordination group that is resistant to oxidation and metal atoms, wherein the double strands are formed by ... 12/14/06 - 20060281907 - Halogenated aminoquinolines and methods for forming dna triplexes Novel synthetic monomers that have the capacity to be assembled into defined oligomers which bind with sequence specificity to duplex Watson-Crick DNA via a triple helix motif are provided. ... 12/07/06 - 20060276635 - Rna interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (sina) The present invention concerns methods and reagents useful in modulating gene expression in a variety of applications, including use in therapeutic, diagnostic, target validation, and genomic discovery applications. Specifically, the invention relates to synthetic chemically modified small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA ... 11/30/06 - 20060270840 - Pentopyranosyl nucleic acid conjugates The invention relates to compounds including at least one pentopyranosyl nucleic acid and a biomolecule conjugated through a covalent linkage to the at least one pentopyranosyl nucleic acid. The pentopyranosyl nucleic acid has at least two pentopyranosyl nucleotide subunits covalently linked between carbon 4 and carbon 2 of their respective ... 11/23/06 - 20060264619 - Plasmodium falciparum ama-1 protein and uses thereof In this application is described the expression and purification of a recombinant Plasmodium falciparum (3D7) AMA-1 ectodomain. The method of the present invention produces a highly purified protein which retains folding and disulfide bridging of the native molecule. The recombinant AMA-1 is useful as a diagnostic reagent, for use in ... 11/16/06 - 20060258855 - High resolution analysis of genetic variation within cryptosporidium parvum An oligonucleotide selected from at least one of the DNA sequences designated SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, and/or SEQ ID NO: 6, or annealing equivalents thereof is described. Also disclosed is a method for the genotypic and subgenotypic identification of the genus Cryptosporidium ... 11/02/06 - 20060247429 - Rna interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (sina) The present invention concerns methods and reagents useful in modulating gene expression in a variety of applications, including use in therapeutic, diagnostic, target validation, and genomic discovery applications. Specifically, the invention relates to synthetic chemically modified small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA ... 11/02/06 - 20060247428 - Rna interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (sina) The present invention concerns methods and reagents useful in modulating gene expression in a variety of applications, including use in therapeutic, diagnostic, target validation, and genomic discovery applications. Specifically, the invention relates to synthetic chemically modified small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA ... 06/29/06 - 20060142557 - 2'-deoxy-2'alkylnucleotide containing nucleic acid 2′-deoxy-2′-alkylnucleotides useful for stabilizing enzymatic nucleic acid molecules and antisense molecules. ... 06/29/06 - 20060142556 - Modulation of oligonucleotide cpg-mediated immune stimulation by positional modification of nucleosides The invention provides methods for modulating the immune response caused by CpG dinucleotide-containing compounds. The methods according to the invention enables both decreasing the immunostimulatory effect for antisense applications, as well as increasing the immunostimulatory effect for immunotherapy applications. ... 04/20/06 - 20060084798 - Cdnas and proteins involved in hypoxia, circadian and orphan signal transduction pathways, and methods of use The present invention provides isolated nucleic acids and proteins that are new and distinct members of the bHLH-PAS superfamily of transcription regulators. These “MOPs” (members of PAS) are useful in a variety of research, diagnostic and therapeutic applications. Several of the MOPs of the present invention are α-class hypoxia-inducible factors. ... 04/20/06 - 20060084797 - High affinity tgfbeta nucleic acid ligands and inhibitors Methods are described for the identification and preparation of high-affinity nucleic acid ligands to TGFβ2. Included in the invention are specific RNA ligands to TGFβ2 identified by the SELEX method. Also included are RNA ligands that inhibit the interaction of TGFβ2 with its receptor. ... 04/20/06 - 20060084796 - Sequence-determined dna encoding methyltransferases The present invention provides DNA molecules that constitute portions of the genome of a plant. The DNA molecules are useful for expressing a gene product, either as a promoter or as a structural gene or as an UTR or as an 3′ termination sequence and are also useful in controlling ... 04/13/06 - 20060079675 - Compositions and use of inflammation-20 (inf-20) gene This invention relates to Inf-20, a novel apoptosis regulator, that in one embodiment is induced by TNF. The gene, designated inflammation-20 (Inf-20), encodes a polypeptide of 184 amino acids. In one embodiment Inf-20 comprises a conserved death effector domain (DED) that is capable of interacting with caspase-8, but not with ... 04/13/06 - 20060079674 - Contraceptive targets The present invention relates generally to ovary-specific genes (O1-180, O1-184 and O1-236) and the proteins they encode. Also provided are methods for detecting cell proliferative or degenerative disorders in reproductive tissues. Yet further, the invention provides methods for scrounge of compounds that interact and/or modulate the expression or activity of ... 04/13/06 - 20060079673 - Polynucleotides encoding trna synthetase fragments and uses thereof The present invention relates to compositions and methods for treating conditions associated with angiogenesis. In particular the present invention relates to polynucleotides encoding a tRNA synthetase fragment, or more two or more tRNA synthetase fragments. ... 04/13/06 - 20060079672 - Kits for modulating angiogenesis The present invention relates to kits for modulating angiogenesis. In some embodiments, a kit of the present invention comprises a container comprising a multi-unit complex wherein at least one unit of said multi-unit complex comprises a tRNA synthetase fragment or a homolog or analog thereof. In some embodiments, a kit ... 04/06/06 - 20060074232 - Matrimony gene and protein The present invention is generally directed to Matrimony (Mtrm) nucleotide sequences, polypeptides expressed from the nucleotide sequences and methods employing the Mtrm nucleotide and polypeptide sequences. The Mtrm nucleotide sequences of the invention express a dosage dependent polypeptide that mediates achiasmate chromosome disjunction. In particular, reduction in the amount of ... 03/23/06 - 20060063924 - Leukocyte regulatory factors 1 and 2 The present invention relates to novel LRF-1 and LRF-2 proteins which are related to the CRISP family and a protein called “Neutrophil Inhibitory Factor (NIF)” isolated from the canine hookworm (Ancylostoma caninum) that potently inhibits CD11/CD18-dependent neutrophil function. In particular, isolated nucleic acid molecules are provided encoding the human LRF-1 ... 03/23/06 - 20060063923 - 4-1bb peptides and methods for use The present invention includes the receptor protein 4-1BB and the cDNA gene encoding for receptor protein 4-1BB. The nucleotide sequence of the isolated cDNA is disclosed herein along with the deduced amino acid sequence. The 4-1BB protein and fragments and derivatives can be used: 1) as a probe to isolate ... 03/16/06 - 20060058517 - Method for the hydrophobisation of dna molecules The present invention relates to a method for the hydrophobisation of DNA molecules comprising mixing an aqueous solution of the DNA molecule with a solution of a cationic lipid or a surfactant in an organic solvent under agitation for a period in the range of 30 to 60 minutes to ... 03/16/06 - 20060058516 - Novel serine-threonine kinase STK3 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing STK3 polypeptides and polynucleotides in diagnostic assays. ... 03/09/06 - 20060052592 - Vaccines for suppressing ige-mediated allergic disease and methods for using the same Nucleic acid molecules that encode a protein comprising at least one epitope of membrane IgE free of epitopes present on the serum IgE, including proteins that further comprise non-IgE T cell helper epitope are disclosed. Vaccines, vectors and host cells that comprise such nucleic acid molecules are disclosed. Isolated proteins, ... 03/09/06 - 20060052591 - Methods and materials relating to carcinoembryonic antigen-like (cea-like) polypeptides and polynucleotides The invention provides novel polynucleotides and polypeptides encoded by such polynucleoddes and mutants or variants thereof that correspond to a novel human secreted CEA-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from rectum (Hyseq clone identification numbers 15456780 (SEQ ID NO: 1)). Other aspects of the ... 02/23/06 - 20060041111 - Dock 3 tumor suppressor gene The invention relates to a newly identified tumor suppressor gene, designated DOS (for Deleted in Osteosarcoma and alternatively referred to herein as DOCK 3) which has been cloned from human and mouse cells. The DOS nucleic acid and protein molecules and their use in the diagnosing and treating disorders characterized ... 02/23/06 - 20060041110 - Enzymatic template polymerization A conductive polymer is formed enzymatically in the presence of a polynucleotide template. The method includes combining at least one redox monomer with a polynucleotide template and a redox enzyme, such as horseradish peroxidase, to form a reaction mixture. The monomer aligns along the template before or during the polymerization. ... 02/16/06 - 20060036088 - Natural promoters for gene expression in c1 metabolizing bacteria Genes have been identified in the Methylomonas genome that are responsive to various metabolic and growth conditions. The identified responsiveness of these genes allows for the use of their promoters in regulated gene expression in C1 metabolizing bacteria. In particular, the hps promoter, which in its native state drives the ... 02/16/06 - 20060036087 - 2'-deoxy-2'-fluoro modified rna The present invention refers to an RNA molecule with catalytic activity comprising at least one modified nucleoside, wherein the hydroxy group at the 2′-position of the ribose sugar is replaced by a modifier group, selected from halo, sulfhydryl, azido, amino, monosubstituted amino and disubstituted amino groups, a process for the ... 02/16/06 - 20060036086 - Use of signal transduction inhibitors and combination therapies for the prevention or treatment of cancer and angiogenesis related diseases The invention provides improved compositions (e.g., combinations of signal transduction inhibitors) and methods for the prevention, stabilization, or treatment of cancer or other angiogenesis related diseases. In particular, the present methods use combination therapies to modulate the expression or activity of multiple mRNA molecules or proteins associated with angiogenesis or ... 02/09/06 - 20060030698 - Nucleic acid molecules and other molecules associated with plants The present invention is in the field of plant biochemistry. More specifically the invention relates to nucleic acid molecules that encode proteins and fragments of proteins produced in plant cells, in particular, soybean plants. The invention also relates to proteins and fragments of proteins so encoded and antibodies capable of ... 01/26/06 - 20060020123 - Gene encoding a protein having aurone synthesis activity The present invention provides a protein having aurone synthase activity involved in the color of flowers such as snapdragons, a gene that encodes it, cDNA in particular, and its applications. This gene can give yellow color to the flowers of plants by introducing into plants deficient in chalcone isomerase and ... 01/26/06 - 20060020122 - Xylanase, microorganisms producing it, dna molecules, methods for preparing this xylanase and uses of the latter The invention relates to a xylanase originating from a Bacillus strain. This xylanase is active over a wide range of acid and basic pH. The invention also relates to new strains of microorganisms producing this xylanase and to methods for preparing this xylanase. The invention also relates to a DNA ... 01/19/06 - 20060014940 - Cloning and characterization of slc26a6, slc26a1, and slc26a2 anion exchangers Isolated nucleic acids encoding SLC26A6, SLC26A1, and SLC26A2 anion transporter polypeptides, recombinantly expressed SLC26A6, SLC26A1, and SLC26A2 anion transporter polypeptides, heterologous expression systems for recombinant expression of SLC26A6, SLC26A1, and SLC26A2 anion transporter polypeptides, assay methods employing the same, and methods for modulation of anion transport activity. ... 01/12/06 - 20060009630 - Compositions and methods for inhibiting squamous cell carcinoma The present invention relates to compositions and methods for detecting and inhibiting squamous cell carcinoma using agents that target the laminin 5 alpha 3 G4-G5 domain. ... 01/12/06 - 20060009629 - Organic light emitting device material and organic light emitting devcie The present invention provides phosphorescent materials and polymer phosphorescent materials that generate lights of various colors including blue, green, yellow, orange and red, which are useful for high performance multicolor organic light-emitting EL devices, and also provides an organic light emitting device material containing a gold complex represented by formulae ... 01/12/06 - 20060009628 - Modified oligonucleotides for mismatch discrimination Modified oligonucleotides are provided containing bases selected from unsubstituted and 3-substituted pyrazolo[3,4-d]pyrimidines and 5-substituted pyrimidines, and optionally have attached minor groove binders and reporter groups. ... 12/29/05 - 20050288497 - Responsiveness to therapy for liver disorders Sets of nucleic acids and methods for predicting a subject's responsiveness to therapy for liver disorders. ... 11/24/05 - 20050261486 - Compositions and methods for binding agglomeration proteins Amplibody compositions and methods used to interact with agglomeration proteins and initiate and mediate an aggregation cascade are disclosed herein. Compositions herein comprise one or more DNA or RNA molecules having affinity for at least one agglomeration protein. The nucleic acid component is a naturally occurring or non-naturally occurring molecule ... 11/24/05 - 20050261485 - Method of producing antisense oligonucleotide The object of the present invention is to provide a method of producing antisense oligonucleotide, in which the possibility of forming a substantially complementary double-stranded chain between each region of a nucleotide sequence in mRNA and a region other than said region is expressed as a numerical value, and oligonucleotide ... 11/10/05 - 20050250937 - Polynucleotide constructs for increased lysine production The invention relates to production of lysine, and provides several isolated polynucleotide molecules useful for the production of L-lysine. One such polynucleotide encodes an aspartate kinase (ask), an aspartate-semialdehyde dehydrogenase (asd) and a dihydrodipicolinate reductase (dapB). Other polypeptides encode ask, asd, dapB and a diaminopimelate dehydrogenase (ddh); ask, asd, dapB, ... 10/20/05 - 20050234227 - Ribosome structure and protein synthesis inhibitors The invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as crystals produced by such methods. The invention also provides high resolution structures of ribosomal subunits either alone or in combination with protein synthesis inhibitors. The invention provides methods for identifying ribosome-related ligands and ... 10/06/05 - 20050222400 - Aptamer constructs Provided are RNA oligonucleotides having an aptamer flanked by two self-cleaving ribozymes. Vectors encoding the oligonucleotides, and cells transfected with these vectors are also provided. Additionally, methods of inhibiting replication of a virus in a cell, methods of treating an organism with an aptamer, methods of determining whether a test ... 10/06/05 - 20050222399 - Bioinformatically detectable group of novel regulatory oligonucleotides associated with alzheimer's disease and uses thereof The present invention relates to a first group of novel oligonucleotides, here identified as genomic address messenger or GAM oligonucleotides, and a second group of novel operon-like polynucleotides, here identified as genomic record or GR polynucleotides. GAM oligonucleotides selectively inhibit translation of known target genes, many of which are known ... 08/11/05 - 20050176942 - Diagnostic tests for a new spirochete, borrelia lonestari sp. nov. Bites from Amblyomma americanum, a hard tick, have been associated with a Lyme disease-like illness in the southeastern and south-central United States. Present in 2% of ticks collected in four states were uncultivable spirochetes. Through use of the polymerase chain reaction, partial sequences of the flagellin and 16s rRNA genes ... 08/11/05 - 20050176941 - Nucleoside analogues whose sugar moieties are bound in s-form and oligonucleotide derivatives comprising nucleotide analogues thereof These compounds are useful for producing oligonucleotide analogues useful for the antisense method, antigene method, etc., and for producing their intermediates. ... 08/11/05 - 20050176940 - Aptamers and antiaptamers The present invention relates to: An aptamer comprising a circular oligonucleotide defining one to four target binding regions; An aptamer comprising an oligonucleotide defining two, three or four thrombin binding quadruplex regions separated by at least partially duplex regions, wherein the quadruplex regions comprise a GGTMGGXGGTTGG sequence wherein M represents ... ### FreshPatents.com Support - Terms & Conditions |